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Cytotoxicity assays conducted on 3T3 fibroblasts, C2C12 myotubes, PC12 neurons, and RAW macrophages, demonstrated that neither Au nanospheres nor Au-PX-PLGA (0.010.5 mg/mL) caused significant toxicity, with cell viability remaining above 95%

While previous studies have primarily focused on standard inflammatory markers, our findings suggest that IF may modulate the immune response at the cellular level, potentially offering a novel mechanism for managing inflammation in RA 26

In addition to superoxide dismutases, catalases, and ascorbate peroxidases, GPxs are important components of the enzymatic systems and are the focus of this article [11] (Table 1)